Technological Hegemony

Luo Jia came to the Ministry of Agriculture, announced that it was officially merged into the Ministry of Life Sciences, and established the main research and development direction with genetic modification.

After a brief introduction, he habitually pulled over the whiteboard and quickly wrote on it, while the others in the conference room stared at each other and looked closely.

Uh ~

Soon after, Luo Jia stopped writing, and two powerful sets of genetic science tools leaped above the whiteboard. One was a gene editing tool called Triassic, and the other was a gene verification tool called Cretaceous.

Both tools come from advanced plant civilization, but in order to be used on the earth, Luo Jia renamed them slightly mysteriously and weakened them appropriately.

After all, as one of the most powerful and oldest civilizations among the stars, the genetic technology of plant civilization is a bit too advanced for the earth, weakening some functions, but it is easy to be accepted by the earth science community, and it may be misunderstood by others. Jia is a traverser.

"It's a bit interesting. I never expected that Luo also knew genetics?"

"Nonsense, Luo is always a rare all-around player. This is something the world has long known."

"This tool seems to be able to accurately overhaul bases?"

"It looks like this, but Luo needs to explain ..."

Everyone talked, the diagram was rather obscure, and they seemed to understand it.

After Luo Jia put down the ink pen, Shen Sheng said, "We need to use gene editing tools if we want to change the genetic order of living things, and the current global gene editing tool research has been developed to the third generation."

"From the first-generation DNA nuclease editing system ZFNs, to the second-generation TALENs, to the third-generation gene editing tool CRISPR / Cas9 system, it is undoubtedly a series of great progress. However, even the most advanced CRISPR technology currently features It's still limited, and there will still be a lot of off-target phenomena. "

"Everyone who has done transgenic engineering understands that, in simple terms, transgene is genetic control, and off-target means that gene mutation is not controlled. It is a very dangerous thing that must be overcome."

"So I conceived a precise gene editing tool. Triassic, Triassic can effectively realize the free conversion of all 12 single bases without the need for additional DNA templates. Delete. According to the data simulation test, Triassic can insert up to 44bp bases and delete 80bp bases. "

"Compared to the third generation CRISPR system, there are two biggest differences in the Triassic. The first is to modify the single-stranded guide RNA (sgRNA). An RNA sequence has been added to the end. The newly obtained RNA, I call it pegRNA. , Secondly, the Cas9 nicking enzyme is fused with reverse transcriptase to obtain a new fusion protein, and then forms a dual role with the terminal sequence of pegRNA ... "

In this world, genetic science is definitely one of the most difficult and obscure disciplines. Luo Jia's words are also full of various obscure technical terms.

There is no need to mention professional matters. It is worth mentioning the idea. This time, Luo Jia was very clever. He did not copy the plant civilization gene editing tools, but instead cleverly integrated with the third-generation tools on the earth, using advanced plant family technology to give The third generation tool adds two new features.

It seems that Luo Jia is only on the research results of his predecessors. Two improvements were made, but these two improvements gave the old tools a finishing touch, and even a huge improvement.

"Great, this is a genius design!"

"With this tool, you can achieve precise genetic control!"

Du Wei, the head of agriculture, has not spoken yet, and Wen Chengfeng shouted loudly. He has seen that after adding two new features, the gene editing tools have become more accurate, and the off-target rate has dropped sharply.

Luo Jia's appearance is light and light, and he does not care so much, because it is really nothing. In fact, Lan Yu's tools are stronger, so powerful that he can even cultivate terrible aliens. plant.

However, based on the principle of gradual progress, Luo Jia only leaked a small part to everyone this time. In the rest of the day, he will continue to knock side by side to lead the company while moving in the right direction until he fully masters the plant family. For gene editing technology, only at key R & D nodes can Luo Jia end in person.

After introducing the gene editing tool, Luo Jia began to introduce the gene verification tool, Cretaceous.

Luo Jia Shen said: "Gene editing tools are like weapons in the hands of soldiers. Weapons do not kill people. Talents can kill people. To ensure that genetic weapons are not abused, we also use genetic verification tools to ensure safety."

"The Cretaceous little artificial intelligence star based on the software department can be regarded as the genetic version of the little star. Whenever we carry out directional editing of biological genes, artificial intelligence will use complex calculations and exhaustion to simulate future implementation. Will there be security risks. "

"The effect of simulating genetic mutations on humans and all living things is completely counter-intuitive, but fortunately, we have a powerful supercomputing system that is sufficient to support the operation of the entire mathematical model ..."

Luo Jia continued to explain technology, and after hearing Luo Jia's words, everyone suddenly realized that the original gene verification system was a mathematical model, plus a genetic algorithm controlled by artificial intelligence.

Suppose you use genetic tools to modify grapes. Humans or other organisms, whether eating this genetically modified grape is harmful, can be calculated by the tool. If it is really harmful, artificial intelligence predicts it in advance.

"Ancient people, if you want to be good, you must first sharpen your tools. If you have these two tools, it will greatly help our work. Do you think my plan is feasible?" Luo Jia looked around and asked .

Everyone nodded again and again without any objections.

Once again seeing Luo Jia's genius idea, the five bodies that everyone admired, the saying goes, highly determines the field of vision, changes the perspective, Luo Jia with cosmic civilization technology as the backing, obviously thinking ahead, seeing the problem more thoroughly than everyone And more long-term.

Luo Jia finally concluded: "In the principle of seeking truth from facts, we must understand a basic fact, that is, the earth's plants must not be able to adapt to the colonies of alien planets, nor to the environment of starships and long journeys."

"Putting wheat on Earth to Mars for farming is probably inactive, so even for the needs of interstellar colony, we must invest in genetically modified plants."

"There is also a starship voyage. If our crew can eat green and fresh vegetables during a long journey, it would be great. The limited resources on the starship are destined that plants cannot be produced as randomly as they can on earth. The plants that follow the starship's voyages must adapt to more demanding living conditions. "

"Coupled with the needs of the transformation of the earth's agriculture, interstellar colonies, voyage starships, and the earth's native land, these three major needs are the research directions of the agricultural sector in the future, and any aspect cannot be ignored."

"In addition, we must also consider the acceptability of the people on the planet. Don't make too exaggerated results. For example, producing 30,000 kilograms per mu is a wonderful vision. But if it is achieved, it is estimated that the vast majority of people will be It scared me not to eat such a high-yield staple. "

"So at this stage, import substitution is still the main method. For example, cherry seeds, we develop our own good seedlings, sell them to domestic agricultural institutions at low prices, and compete with international seedling suppliers to drive them out of the market. Go out. "

"You also know that in another two months, the space elevator will be completed. I hope you will add a bright color to the synchronous orbital station and even the lunar base. Let us be in charge of stationing in space and mining helium on the moon. Colleagues from San, how much more interesting life can be. "

Drawing a big cake is a skill. Luo Jia was very smart to guide the future of the Ministry of Agriculture in the direction of space. After listening to his words, the colleagues of the Ministry of Agriculture were so excited that they couldn't control themselves. It's wonderful to contribute to the company's space program.

In general, Luo Jia's plan is very simple. No one can stop the genetic modification. It must be done. This is the company's unshakable goal.

However, there must be a strategy for genetic modification. The earth should be low-key, and some domestic alternatives to imported seedlings should be given to the people. You can choose to trust Xingchen Technology and eat genetically modified food. If you don't trust, you will not eat it. The decision is left to the masses.

However, when it comes to the space program led by Xingchen Technology, there is no choice. Just kidding, agricultural technology is not developing. How can we expand our territory beyond the earth in the future?

As long as you participate in Star Technology ’s space program ~ www.wuxiahere.com ~, then it is necessary to follow the rules of Star Technology. Genetic modification in the space program is not an option, but a necessity.

"Guaranteed!"

"Cultivate powerful new plants for the space program? We are willing to do this job!"

"I haven't seen Meng Shan pleasing to the eye, I just had a deal with them!"

Everyone spoke excitedly. Luo Jia nodded with satisfaction and said something of encouragement, then turned away. After all, although agriculture is important, it is a typical slow-heating project. It is impossible for Luo Jia to arrange it in the short term. Can see results.

Two advanced genetic tools have been handed over to them. Next, the agricultural sector needs to play it out. To what extent, Luo Jia is not prepared to ask. Anyway, as long as it can ensure safety, it will do its best.

Stepping out of the door of the Ministry of Agriculture and looking at the big sun at noon, Luo Jia couldn't help feeling that time passed so fast, unknowingly, that the seventh year since the founding of the company was almost over.

For Luo Jia, this new year is of special significance because the completion of the space elevator and synchronous orbital station is just at the end of the year.